Definition
A sore throat is pain anywhere in the oropharynx.[1]
Differential diagnosis
A sore throat is usually from irritation or inflammation. The most common cause (80%) is acute viral pharyngitis, a viral infection of the throat.[1] Other causes include other infections (such as streptococcal pharyngitis), trauma, and tumors.[1] Gastroesophageal (acid) reflux disease can cause stomach acid to back up into the throat and also cause the throat to become sore.[2] In children streptococcal pharyngitis is the cause of 37% of sore throats.[3]Sore throat is a generic term used to describe the symptom of discomfort and pain in the throat area. It does not specify the underlying cause.
Strep throat is a bacterial infection of the throat and tonsils that causes a sore throat. It is important to note that not all cases of sore throat are necessarily strep throat. Strep throat is specifically caused by group A Streptococcus bacteria, and there are characteristic signs and symptoms, as well as laboratory testing, that can assist in making this particular diagnosis.
What are the causes of sore throat?
- Viral infection: This is by far the most common cause of a sore throat, and there are several different viruses that can lead to the common cold and an upper respiratory infection. Certain viruses such as the influenza virus (influenza, flu), Epstein-Barr virus (mononucleosis), mumps virus (mumps), parainfluenza virus (croup) and Coxsackie A virus (herpangina) also cause sore throat.
- Bacterial infection: A less common cause of sore throat, a bacterial infection can lead to strep throat, peritonsillar abscess, retropharyngeal abscess, diphtheria, epiglottitis, and tonsillitis. Certain sexually transmitted diseases (STD's), such as gonorrhea and chlamydia, also can rarely cause a sore throat.
- Toxins/Irritants: Various substances such a cigarette smoke, air pollution, and noxious airborne chemicals can lead to a sore throat. Medical conditions such as postnasal drip, allergies, cough, gastroesophageal reflux disease (GERD), and tumors can cause a sore throat. The intentional or unintentional ingestion of certain substances (for example, bleach) can cause a sore throat.
- Trauma/Injury: Any direct injury to the throat or neck area can lead to a sore throat. Sometimes, a foreign body (for example, a bone or piece of food) can cause a sore throat. Excessive yelling or screaming can irritate the throat and larynx, also leading to a sore throat
Signs and symptoms
- painful and swollen tonsils
- tender and swollen glands in your neck
- painful, tender sensation at the back of your throat
- discomfort when swallowing
- a high temperature (fever)
- chills
- headache
- tiredness
- aching muscles
- runny nose
- coughing
- sneezing
- general feeling of being unwell
- refusing to feed
- irritability
- frequent crying
- high temperature
- cough
- difficulty sleeping
- sneezing
- runny nose
- diarrhea
- tiredness and feeling generally unwell


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